Nerve growth factor upregulates sirtuin 1 expression in cholestasis: a potential therapeutic target
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منابع مشابه
Nerve growth factor upregulates sirtuin 1 expression in cholestasis: a potential therapeutic target
This study investigated the regulatory role of nerve growth factor (NGF) in sirtuin 1 (SIRT1) expression in cholestatic livers. We evaluated the expression of NGF and its cognate receptors in human livers with hepatolithiasis and the effects of NGF therapy on liver injury and hepatic SIRT1 expression in a bile duct ligation (BDL) mouse model. Histopathological and molecular analyses showed that...
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ژورنال
عنوان ژورنال: Experimental & Molecular Medicine
سال: 2018
ISSN: 1226-3613,2092-6413
DOI: 10.1038/emm.2017.235